Cardiopulmonary Findings in a Newborn for USMLE

In Episode 7 of Med School Question of the Week for USMLE, Leigh Finnegan answers the following:

A 37-year-old G1P1001 delivers a 38-week female infant via spontaneous vaginal delivery. At birth, the infant is noted to have slanted palpebral fissures, a single palmar crease, and a wide gap between the first and second toes. A murmur is auscultated on cardiac exam, and a congenital heart defect is suspected. What is most likely to be present on further evaluation?

• Narrowing of the aorta
• Severe regurgitation between the ventricles and the atria
• Pulmonary stenosis with overriding aorta
• Abnormal connection between the pulmonary artery and the aorta