In Episode 6 of Med School Question of the Week for USMLE, Luke Maxfield, MedSchoolCoach expert tutor, answers this medical school question: A physician is in the process of developing a serologic test to determine the presence of sarcoidosis. While evaluating this study serum levels of Anti-X- protein will be measured. The presence of Anti-x-protein will be compared to tissue biopsies demonstrating non-caseating granulomas as the control. 200 patients were recruited and 120 had positive biopsy results. Anti-X protein was found in 80 patients with sarcoidosis and was positive in 15 patients without the disease. What is the specificity of the test?
Luke obtained his B.S. from the University of Colorado while working at the University of Colorado Anschutz Medical Campus department of pathology as a student researcher. He completed studies at the University of Tennessee at Chattanooga and is a current dermatology resident. Luke scored in the 99th percentile on his COMLEX exams.