USMLE Question of the Week

Understanding Antiretroviral Combination Therapy

In Episode 32 of Med School Question of the Week for USMLE, Alisa Khomutova, MedSchoolCoach expert tutor, answers this medical school question: A 47-year-old man comes to the physician for a routine health maintenance exam. He was diagnosed with HIV 16 years ago. He was taking triple antiretroviral therapy but stopped a few months ago because he was feeling fine. He lives in Mississippi. Vital sign and physical exam are normal. His CD4+ and T-lymphocyte count is 47/mm (n ≥ 500). The patient refuses to restart antiretroviral therapy. Which of the following medication regiments is most appropriate at this time?
  • Azithromycin
  • Trimethoprim + sulfamethoxazole
  • Amphotericin B
  • Dapsone
  • Trimethoprim, sulfamethoxazole, azithromycin
  • Trimethoprim, sulfamethoxazole, azithromycin, amphotericin B
Click to Reveal the Correct Answer

Trimethoprim, sulfamethoxazole, azithromycin

Alisa Khomutova

Alisa received her B.S. from University of California, Davis, and attended Oakland University William Beaumont School of Medicine. In 2020, she matched into Stony Brook Teaching Hospital practicing General Surgery for residency.

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