MCAT Basics Podcast

Metabolism: Glycolysis, Krebs Cycle, Electron Transport Chain

In this episode, Sam Smith covers the intricacies of metabolism, focusing on glycolysis, the Krebs cycle, and the electron transport chain. 

First, the podcast explores the process of glycolysis, breaking down the key enzymes, intermediates, and regulation points. Next is the citric acid cycle, examining its regulation, energy production, and the roles of specific enzymes and intermediates. Lastly, we look at the electron transport chain and discuss how electrons are transferred through the five complexes, creating a proton gradient that drives ATP synthase to produce ATP. 

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Jump into the conversation:

(00:00) Intro

(03:15) Ten steps of glycolysis: Intermediate names and enzymes

(08:01) Simplified glycolysis process: Breaking down key steps

(12:30) Glycolysis regulation: Allosteric regulation of enzymes

(21:13) Mnemonics for Krebs cycle intermediates

(25:52) Regulation of the Krebs cycle: ATP, calcium, and more

(30:26) Electron transport chain: Overview and key steps

(34:35) ATP synthase

(33:00) Reduction potentials in the electron transport chain

(37:31) Synopsis of metabolism

(40:34) MCAT Advice of the Day

Sam Smith

Sam completed his Bachelors of Science in Chemical and Biological Engineering at the University of Colorado Boulder. Following his graduation, he worked at the National Institutes of Health Vaccine Research Center studying HIV. Meanwhile, with a microphone in his garage, Sam founded the MCAT Basics podcast. The podcast has grown to become the top rated MCAT podcast on iTunes. In addition to podcasting, Sam enjoys the outdoors, sports, and his friends and family.

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