Understanding Antiretroviral Combination Therapy

In Episode 32 of Med School Question of the Week for USMLE, Alisa Khomutova, MedSchoolCoach expert tutor, answers this medical school question: A 47-year-old man comes to the physician for a routine health maintenance exam. He was diagnosed with HIV 16 years ago. He was taking triple antiretroviral therapy but stopped a few months ago because he was feeling fine. He lives in Mississippi. Vital sign and physical exam are normal. His CD4+ and T-lymphocyte count is 47/mm (n ≥ 500). The patient refuses to restart antiretroviral therapy. Which of the following medication regiments is most appropriate at this time?

• Azithromycin
• Trimethoprim + sulfamethoxazole
• Amphotericin B
• Dapsone
• Trimethoprim, sulfamethoxazole, azithromycin
• Trimethoprim, sulfamethoxazole, azithromycin, amphotericin B